And thou hast filled me with wrinkles. So St. Jerome, Professor Lee, Dr. Stanley Leathes, and others; but the generality of modern commentators prefer the rendering, "Thou hast bound me fast," i.e. deprived me of all power of resisting or moving (comp.
Psalms 88:8, "I am so fast in prison that I cannot get forth"). Which is a witness against me; i.e. a witness of thy displeasure, and so (as men suppose) of my guilt. And my leanness rising up in me heareth witness to my face; rather, my leanness rising up against me.
This emaciation is taken as another witness of his extreme sinfulness.