Whither shall I go from thy spirit? or whither shall I flee from thy presence? The transition is now made from God's omniscience to God's omnipresence, Psalms 139:5 having paved the way for it. God's presence is not to be escaped; his spirit is everywhere.
"In him we live, and move, and have our being" (Acts 17:28). When Jonah sought to flee from his presence, he only found himself brought more absolutely and more perceptibly into his presence (comp. Jeremiah 23:24).