Fellowship with me will involve separation from the dearest upon earth, yet the reward is great. (Cf. Matthew 10:5, note.) The progress of thought in these verses seems to be as follows: Do not be surprised at the contradiction that appears between my teaching and the immediate result; I allowed for this when I began my work (Matthew 10:34).
There will, indeed, be separation in the closest earthly ties (Matthew 10:35, Matthew 10:36). But my claims are paramount (Matthew 10:37, Matthew 10:38). And on your relation to them depends everything hereafter (Matthew 10:39).